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How a little box is preserving hearts and saving lives

CHICAGO (WGN) — Seventy percent of donor hearts go unused every year. That means people in need never get the lifesaving organ, and people who so generously donated never get the chance to have their gift of life recognized upon their death.

Doctors are now breaking through the biggest barriers for heart transplantation with a new device.

“We typically have about four hours to get from the time we retrieve organ to implantation into recipient,” Dr Jane Wilcox, chief of Heart Failure Treatment and Recovery at Northwestern Medicine, said of standard hypothermic preservation procedures, which limit organ viability.

Enter the Transmedics Organ Care System — or the "heart in the box," as it's been nicknamed.

“You can then put that organ on this ‘heart in a box’ and the box has the donor's blood and it perfuses and sort of pumps the heart,” Wilcox said.

The portable box — which looks somewhat like a Tupperware container — has high-tech capabilities.

“It’s several steps above the Igloo cooler in that it’s really simulating what the body is like in terms of temp, environment,” Wilcox said. “It’s being perfused with blood and not a solution. And so that allows us to have extended time, over double the time we would have for a typical window to perform a transplant.”

This device can also give doctors a chance to check the organ in action.

“It’s a very fancy, sophisticated perfusing system,” Wilcox said. “It’s just crazy to see this heart pumping in a box. And you can assess all the characteristics that are important that we consider before doing the transplant.”

All of this opens the door for more donor hearts to be considered an option for transplant. Instead of only choosing hearts from people who are brain dead, the new system resuscitates a stopped heart.

“This ‘heart in a box’ really overcomes those barriers to use more organs,” Wilcox said.

It's a first for Illinois surgeons at Northwestern Medicine's Bluhm Cardiovascular Institute.

“So excited, so grateful, so honored,” Wilcox said. “It’s just wonderful to be part of an amazing team and seeing our patient who has waited a long time, who was really excited to be part of this process, is icing on the cake.”

Jerry Dorsey, 55, is thrilled to be part of history and thankful for the gift of a heart.

“You want that silver lining of when you pass away, for whatever reason, you can provide hope and provide life to another person,” Dorsey said. “We all want to feel useful.”

It's estimated the “heart in a box” device will increase the number of hearts available for transplant by 30%.


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